Across TCGA patient cohorts, GALT mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALT-associated genes across cancer lineages are IGFBP2, Ku80, and MSH2. Each is linked with GALT in more than 1 cancer types. Because this analysis shows association rather than direction, both GALT-to-partner and partner-to-GALT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALT→partner) and Y-score (partner→GALT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGFBP2 →	-0.816	-3.459	.012	.005	3	1
UCEC	Ku80 →	+0.354	+3.009	.002	.019	3	1
UCEC	MSH2 →	-0.375	-2.990	.001	.036	3	1
UCEC	Tuberin →	+0.315	+2.817	.019	.036	3	1
UCEC	VEGFR2 →	+0.429	+2.999	.004	.035	3	1
UCEC	4E-BP1 →	+0.401	+3.029	.003	.018	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

GALT survival (RNA) · tumor vs normal (RNA) · all GALT data types