GALR2

Across TCGA cell cohorts, GALR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,747 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GALR2-associated GO terms across cancer lineages are Regulation of proteasomal protein catabolic process, Adenylate cyclase-modulating G protein-coupled receptor signaling pathway, and Protein insertion into ER membrane. Each is linked with GALR2 in more than 11 cancer types. Because this analysis shows association rather than direction, both GALR2-to-partner and partner-to-GALR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of proteasomal protein catabolic process grouped by GALR2-low versus GALR2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GALR2→partner) and Y-score (partner→GALR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of proteasomal protein catabolic process →	+0.035	+0.261	<.001	.004	3	12
UPPER_AERODIGESTIVE_TRACT	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.067	-0.439	<.001	.009	3	11
SKIN	Protein insertion into ER membrane →	+0.092	+0.134	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of DNA-templated transcription, elongation →	+0.111	+0.550	<.001	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of transcription elongation by RNA polymerase II →	+0.124	+0.467	<.001	.009	3	9
KIDNEY	Ribonucleoside triphosphate biosynthetic process →	+0.059	+0.180	.001	.004	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,747 associations by consensus.

Regulation of proteasomal protein catabolic process by GALR2 expression — BREAST

Explore this box plot interactively →