GALR1

Across TCGA patient cohorts, GALR1 mutation is significantly associated with the RNA expression of many other genes, with 2,674 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GALR1-associated genes across cancer lineages are RNA5SP459, GINS3, and RPL35AP33. Each is linked with GALR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GALR1-to-partner and partner-to-GALR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP459 grouped by GALR1-low versus GALR1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALR1→partner) and Y-score (partner→GALR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5SP459 →	+0.180	+4.816	<.001	.001	3	3
UCEC	GINS3 →	+0.554	+2.758	<.001	<.001	3	3
COAD	RPL35AP33 →	+0.189	+3.635	.004	.001	3	3
UCEC	MYO19 →	+0.510	+2.736	<.001	<.001	3	2
SKCM	ST13 →	+0.495	+3.347	.008	.004	3	2
SKCM	CEP76 →	+0.385	+2.379	.006	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,674 associations by consensus.

RNA5SP459 by GALR1 expression — SKCM

Explore this box plot interactively →