GALR1

Across TCGA patient cohorts, GALR1 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALR1-associated genes across cancer lineages are ACC_pS79, Chk1, and DJ-1. Each is linked with GALR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GALR1-to-partner and partner-to-GALR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC_pS79 grouped by GALR1-low versus GALR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALR1→partner) and Y-score (partner→GALR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC_pS79 →	+0.431	+3.700	.001	.001	3	2
SKCM	Chk1 →	+0.245	+2.034	.004	.017	3	2
SKCM	DJ-1 →	-0.211	-3.000	.009	.034	3	2
UCEC	Annexin_VII →	-0.137	-2.000	.012	.010	3	2
UCEC	CD31 →	-0.163	-2.502	.004	.002	3	2
UCEC	4E-BP1 →	+0.427	+2.502	<.001	.002	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

ACC_pS79 by GALR1 expression — UCEC

Explore this box plot interactively →