GALR1

Across TCGA cell cohorts, GALR1 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GALR1-associated genes across cancer lineages are CLEC20A, OR2T7, and ACSM6. Each is linked with GALR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALR1-to-partner and partner-to-GALR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLEC20A grouped by GALR1-low versus GALR1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALR1→partner) and Y-score (partner→GALR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CLEC20A →	+0.034	+4.817	<.001	.001	3	1
LUNG_SCLC	OR2T7 →	+0.005	+4.643	<.001	.004	3	1
LARGE_INTESTINE	ACSM6 →	+0.031	+4.584	<.001	<.001	3	1
LARGE_INTESTINE	CFHR2 →	+0.046	+4.437	<.001	.004	3	1
LUNG_NSCLC_LUAD	TGM7 →	+0.006	+4.887	<.001	.009	3	1
BLOOD_Leukemia	TCF21 →	+0.008	+3.705	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

CLEC20A by GALR1 expression — LUNG_SCLC

Explore this box plot interactively →