GALNTL6

Across TCGA patient cohorts, GALNTL6 mutation is significantly associated with the RNA expression of many other genes, with 1,958 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNTL6-associated genes across cancer lineages are SURF2, DPM2, and CENPH. Each is linked with GALNTL6 in more than 4 cancer types. Because this analysis shows association rather than direction, both GALNTL6-to-partner and partner-to-GALNTL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SURF2 grouped by GALNTL6-low versus GALNTL6-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNTL6→partner) and Y-score (partner→GALNTL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SURF2 →	+0.440	+2.761	<.001	<.001	3	5
SKCM	DPM2 →	+0.362	+3.025	.001	<.001	3	4
UCEC	CENPH →	+0.519	+1.856	.001	.004	3	4
UCEC	ZMYND19 →	+0.488	+2.091	<.001	<.001	3	4
UCEC	POMT1 →	+0.299	+1.856	.005	.004	3	4
UCEC	WDR5 →	+0.368	+2.091	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,958 associations by consensus.

SURF2 by GALNTL6 expression — SKCM

Explore this box plot interactively →