GALNTL6

Across TCGA patient cohorts, GALNTL6 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNTL6-associated genes across cancer lineages are AMPK_pT172, Caspase-7-cleavedD198, and AMPK_alpha. Each is linked with GALNTL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNTL6-to-partner and partner-to-GALNTL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMPK_pT172 grouped by GALNTL6-low versus GALNTL6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNTL6→partner) and Y-score (partner→GALNTL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AMPK_pT172 →	+0.287	+1.750	.043	.004	3	2
UCEC	Caspase-7-cleavedD198 →	+0.667	+2.242	.001	.005	3	2
LUAD	AMPK_alpha →	-0.169	-3.169	.045	.019	3	1
BLCA	Rad50 →	+0.194	+3.000	.029	.036	3	1
SKCM	Smad4 →	+0.119	+2.619	.005	.004	3	1
UCEC	Myosin-IIa_pS1943 →	+0.200	+1.453	.005	.015	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

AMPK_pT172 by GALNTL6 expression — UCEC

Explore this box plot interactively →