GALNTL6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GALNTL6 mutation is significantly associated with the RNA expression of many other genes, with 197 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GALNTL6-associated genes across cancer lineages are KRTAP10-10, KRT71, and PBOV1. Each is linked with GALNTL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNTL6-to-partner and partner-to-GALNTL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP10-10 grouped by GALNTL6-low versus GALNTL6-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNTL6→partner) and Y-score (partner→GALNTL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSKRTAP10-10 →+0.020+4.906<.001.00631
BLOOD_LymphomaKRT71 →+0.009+4.643<.001.00531
SKINPBOV1 →+0.009+3.196.006.00731
LARGE_INTESTINERAB3A →+0.969+3.299.001.00431
LARGE_INTESTINESH3GL2 →+1.345+3.667<.001<.00131
LARGE_INTESTINEPCCB →+0.647+3.125<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 197 associations by consensus.

KRTAP10-10 by GALNTL6 expression — OESOPHAGUS

Box plot of KRTAP10-10 in GALNTL6-low vs GALNTL6-high samples in OESOPHAGUS.

Explore this box plot interactively →

Exploration