GALNTL5

Across TCGA patient cohorts, GALNTL5 mutation is significantly associated with the RNA expression of many other genes, with 2,649 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNTL5-associated genes across cancer lineages are PHB, PPP2R2D, and BNIP1. Each is linked with GALNTL5 in more than 2 cancer types. Because this analysis shows association rather than direction, both GALNTL5-to-partner and partner-to-GALNTL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PHB grouped by GALNTL5-low versus GALNTL5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNTL5→partner) and Y-score (partner→GALNTL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PHB →	+0.506	+2.137	.001	.001	3	3
UCEC	PPP2R2D →	+0.296	+3.763	.001	<.001	3	3
UCEC	BNIP1 →	+0.308	+2.523	.001	<.001	3	3
SKCM	PCGF1 →	+0.296	+2.006	.006	.001	3	3
UCEC	GOT1 →	+0.396	+2.587	.001	<.001	3	3
UCEC	UBE2SP2 →	+0.470	+2.616	.002	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,649 associations by consensus.

PHB by GALNTL5 expression — UCEC

Explore this box plot interactively →