GALNT9

Across TCGA patient cohorts, GALNT9 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT9-associated genes across cancer lineages are eIF4E, JNK2, and Gab2. Each is linked with GALNT9 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT9-to-partner and partner-to-GALNT9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by GALNT9-low versus GALNT9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT9→partner) and Y-score (partner→GALNT9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.193	+3.335	.012	.005	3	2
UCEC	JNK2 →	+0.271	+2.247	<.001	.001	3	2
COAD	Gab2 →	-0.377	-2.296	.010	.035	3	1
COAD	Smad4 →	+0.139	+3.000	.020	.035	3	1
UCEC	14-3-3_beta →	-0.100	-1.489	.006	.030	3	1
UCEC	EGFR_pY1068 →	-0.215	-1.847	.020	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

eIF4E by GALNT9 expression — UCEC

Explore this box plot interactively →