GALNT6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GALNT6 mutation is significantly associated with the RNA expression of many other genes, with 2,405 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT6-associated genes across cancer lineages are SDHCP1, MSANTD3, and RN7SKP252. Each is linked with GALNT6 in more than 2 cancer types. Because this analysis shows association rather than direction, both GALNT6-to-partner and partner-to-GALNT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SDHCP1 grouped by GALNT6-low versus GALNT6-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT6→partner) and Y-score (partner→GALNT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADSDHCP1 →+0.250+3.734<.001.00333
UCECMSANTD3 →+0.582+2.818<.001<.00133
COADRN7SKP252 →+0.315+4.927<.001.00233
COADH3P34 →+0.284+4.109<.001.00733
COADMIR8076 →+0.571+4.109<.001.00733
UCECRNU6-1213P →+0.213+3.555<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,405 associations by consensus.

SDHCP1 by GALNT6 expression — LUAD

Box plot of SDHCP1 in GALNT6-low vs GALNT6-high samples in LUAD.

Explore this box plot interactively →

Exploration