GALNT6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GALNT6 mutation is significantly associated with the RNA expression of many other genes, with 65 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GALNT6-associated genes across cancer lineages are C6orf118, SFT2D3, and OR10T2. Each is linked with GALNT6 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT6-to-partner and partner-to-GALNT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by GALNT6-low versus GALNT6-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT6→partner) and Y-score (partner→GALNT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaC6orf118 →+0.031+4.772.006<.00132
BLOOD_LeukemiaSFT2D3 →+0.464+3.450<.001.00432
BLOOD_LeukemiaOR10T2 →+0.626+3.691<.001.00232
URINARY_TRACTTGM7 →+0.013+5.087<.001.00431
OESOPHAGUSOR2T2 →+0.006+4.906<.001.00631
BLOOD_LeukemiaEPPIN →+0.004+3.922.004.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

C6orf118 by GALNT6 expression — BLOOD_Leukemia

Box plot of C6orf118 in GALNT6-low vs GALNT6-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration