GALNT5

Across TCGA pan-cancer cohorts, GALNT5 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated GALNT5 data layer compared with 26 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher GALNT5 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated GALNT5 expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.

COAD, LUAD, and CCRCC are the cancer types where GALNT5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.885	.018	42	view →
LUAD	DFS	Median	All	0.830	0.970	.011	16	view →
CCRCC	OS	Quartile	II,III,IV	0.975	0.302	.018	11	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	9	view →
HNSC	DFS	Quartile	All	0.458	0.978	.038	6	view →
LSCC	DFS	Quartile	II,III,IV	0.575	0.890	.020	3	view →
GBM	OS	Quartile	All	0.774	0.296	.027	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

GALNT5–COAD (DFS)

Open the COAD breakdown →