GALNT5

Across TCGA patient cohorts, GALNT5 mutation is significantly associated with the RNA expression of many other genes, with 4,834 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT5-associated genes across cancer lineages are CENPH, MIS18A, and CHAF1B. Each is linked with GALNT5 in more than 3 cancer types. Because this analysis shows association rather than direction, both GALNT5-to-partner and partner-to-GALNT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPH grouped by GALNT5-low versus GALNT5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT5→partner) and Y-score (partner→GALNT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPH →	+0.746	+2.233	<.001	<.001	3	3
UCEC	MIS18A →	+0.508	+2.436	<.001	.001	3	3
UCEC	CHAF1B →	+0.834	+2.536	<.001	<.001	2	4
UCEC	ZNF668 →	+0.408	+2.225	.001	.001	3	3
UCEC	MRPL58 →	+0.307	+2.218	.001	.001	3	3
SKCM	TSEN34 →	+0.367	+3.713	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,834 associations by consensus.

CENPH by GALNT5 expression — UCEC

Explore this box plot interactively →