GALNT5

Across TCGA patient cohorts, GALNT5 mutation is significantly associated with the total protein of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT5-associated genes across cancer lineages are Ku80, MEK1, and Mre11. Each is linked with GALNT5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT5-to-partner and partner-to-GALNT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by GALNT5-low versus GALNT5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT5→partner) and Y-score (partner→GALNT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.227	+1.820	.004	.002	3	2
UCEC	MEK1 →	+0.436	+2.137	<.001	.001	3	2
UCEC	Mre11 →	-0.089	-3.673	.002	.001	3	2
UCEC	Notch1 →	+0.158	+2.235	<.001	.005	3	2
UCEC	Akt_pT308 →	+0.597	+2.222	.005	.009	3	2
UCEC	Rab11 →	-0.120	-2.700	.015	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

Ku80 by GALNT5 expression — UCEC

Explore this box plot interactively →