GALNT5

Across TCGA cell cohorts, GALNT5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,084 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GALNT5-associated GO terms across cancer lineages are Negative regulation of actin filament depolymerization, Actin filament capping, and Cell-substrate junction organization. Each is linked with GALNT5 in more than 12 cancer types. Because this analysis shows association rather than direction, both GALNT5-to-partner and partner-to-GALNT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of actin filament depolymerization grouped by GALNT5-low versus GALNT5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT5→partner) and Y-score (partner→GALNT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of actin filament depolymerization →	+0.202	+2.115	<.001	<.001	3	13
BONE	Actin filament capping →	+0.243	+2.204	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Cell-substrate junction organization →	+0.172	+3.150	<.001	.001	3	11
BONE	Positive regulation of protein localization to plasma membrane →	+0.141	+2.991	<.001	<.001	3	11
BREAST	Positive regulation of exosomal secretion →	+0.097	+0.844	.001	.008	3	11
BREAST	Positive regulation of leukocyte migration →	+0.096	+1.135	.002	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,084 associations by consensus.

Negative regulation of actin filament depolymerization by GALNT5 expression — BONE

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