GALNT5

Across TCGA cell cohorts, GALNT5 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GALNT5-associated genes across cancer lineages are MC3R, DEFB124, and OR56A1. Each is linked with GALNT5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT5-to-partner and partner-to-GALNT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MC3R grouped by GALNT5-low versus GALNT5-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT5→partner) and Y-score (partner→GALNT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MC3R →	+0.446	+4.108	.009	.005	3	1
LUNG_NSCLC_LUSC	DEFB124 →	+0.187	+4.108	<.001	.005	3	1
BLOOD_Lymphoma	OR56A1 →	+0.049	+4.523	<.001	.004	3	1
BLOOD_Lymphoma	OR52L1 →	+0.084	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	KRTAP1-4 →	+0.067	+5.247	<.001	.001	3	1
BLOOD_Lymphoma	MYH4 →	+0.019	+5.169	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

MC3R by GALNT5 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →