GALNT3

Across TCGA pan-cancer cohorts, GALNT3 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated GALNT3 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher GALNT3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated GALNT3 expression acts as an unfavorable survival marker, although some lineages such as COAD and HNSC show a favorable association.

COAD, CCRCC, and HNSC are the cancer types where GALNT3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	1.000	0.840	.021	30	view →
CCRCC	DFS	Tertile	III,IV	0.198	0.915	.010	9	view →
HNSC	DFS	Median	II,III,IV	0.847	0.707	.008	5	view →
LSCC	DFS	Quartile	All	0.511	0.823	.025	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

GALNT3–COAD (DFS)

Open the COAD breakdown →