GALNT3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GALNT3 mutation is significantly associated with the RNA expression of many other genes, with 3,007 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT3-associated genes across cancer lineages are RN7SL134P, ARHGAP11A, and PRC1. Each is linked with GALNT3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GALNT3-to-partner and partner-to-GALNT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by GALNT3-low versus GALNT3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT3→partner) and Y-score (partner→GALNT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL134P →+0.084+1.763.002.00733
UCECARHGAP11A →+0.611+1.847<.001<.00133
UCECPRC1 →+0.694+2.115<.001<.00133
UCECRNA5SP369 →+0.247+1.608.002.00833
UCECRNU6-218P →+0.381+1.801<.001<.00133
UCECSAP30 →+0.560+2.436<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,007 associations by consensus.

RN7SL134P by GALNT3 expression — UCEC

Box plot of RN7SL134P in GALNT3-low vs GALNT3-high samples in UCEC.

Explore this box plot interactively →

Exploration