GALNT3

Across TCGA cell cohorts, GALNT3 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GALNT3-associated genes across cancer lineages are MAGEB4, DMRTB1, and MBD3L5. Each is linked with GALNT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT3-to-partner and partner-to-GALNT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by GALNT3-low versus GALNT3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT3→partner) and Y-score (partner→GALNT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.012	+3.678	<.001	.001	3	2
LUNG_NSCLC_LUAD	DMRTB1 →	+0.006	+4.887	<.001	.009	3	1
SKIN	MBD3L5 →	+0.029	+5.415	<.001	.004	3	1
BLOOD_Leukemia	LCE1C →	+0.432	+4.922	.002	.009	3	1
BLOOD_Leukemia	TMEM114 →	+0.044	+5.539	<.001	.003	3	1
BLOOD_Leukemia	SLC5A8 →	+0.182	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

MAGEB4 by GALNT3 expression — LARGE_INTESTINE

Explore this box plot interactively →