GALNT3

Across TCGA cell cohorts, GALNT3 mutation is significantly associated with the mutation status of many other genes, with 6,320 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GALNT3-associated genes across cancer lineages are KSR2, BBS9, and TTC7B. Each is linked with GALNT3 in more than 3 cancer types. Because this analysis shows association rather than direction, both GALNT3-to-partner and partner-to-GALNT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KSR2 grouped by GALNT3-low versus GALNT3-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT3→partner) and Y-score (partner→GALNT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	KSR2 →	+4.954	+4.392	.008	.008	1	4
LARGE_INTESTINE	BBS9 →	+3.392	+3.632	<.001	<.001	1	4
SKIN	TTC7B →	+5.392	+4.824	.004	.004	1	4
LARGE_INTESTINE	KANK4 →	+2.321	+2.643	.004	.004	1	4
BLOOD_Leukemia	LRRIQ1 →	+3.020	+4.545	.004	.004	1	4
LARGE_INTESTINE	CNTN6 →	+2.347	+4.479	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,320 associations by consensus.

KSR2 by GALNT3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →