GALNT2

Across TCGA patient cohorts, GALNT2 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT2-associated genes across cancer lineages are 14-3-3_beta, PCNA, and Caspase-7-cleavedD198. Each is linked with GALNT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT2-to-partner and partner-to-GALNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by GALNT2-low versus GALNT2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT2→partner) and Y-score (partner→GALNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.073	-2.088	.030	.016	3	2
UCEC	PCNA →	+0.199	+1.807	.006	.024	3	2
UCEC	Caspase-7-cleavedD198 →	+0.764	+2.201	<.001	<.001	3	2
UCEC	4E-BP1 →	+0.287	+1.874	.001	.002	3	2
UCEC	C-Raf →	+0.130	+2.087	.006	.005	3	2
UCEC	EGFR_pY1068 →	-0.191	-1.584	.023	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

14-3-3_beta by GALNT2 expression — UCEC

Explore this box plot interactively →