GALNT2

Across TCGA cell cohorts, GALNT2 mutation is significantly associated with the RNA expression of many other genes, with 497 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GALNT2-associated genes across cancer lineages are OR13D1, ADAM7, and PHF5A. Each is linked with GALNT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT2-to-partner and partner-to-GALNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13D1 grouped by GALNT2-low versus GALNT2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT2→partner) and Y-score (partner→GALNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR13D1 →	+0.030	+3.930	<.001	.003	3	2
SKIN	ADAM7 →	+0.011	+5.099	<.001	<.001	3	2
LARGE_INTESTINE	PHF5A →	+0.570	+3.628	<.001	<.001	3	1
LARGE_INTESTINE	FZD3 →	+0.790	+3.628	<.001	<.001	3	1
LARGE_INTESTINE	ARMC1 →	+0.422	+3.067	.002	.009	3	1
LARGE_INTESTINE	SH3GL2 →	+1.069	+2.502	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 497 associations by consensus.

OR13D1 by GALNT2 expression — SKIN

Explore this box plot interactively →