GALNT18

Across TCGA patient cohorts, GALNT18 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT18-associated genes across cancer lineages are ASNS, EGFR_pY1068, and Gab2. Each is linked with GALNT18 in more than 2 cancer types. Because this analysis shows association rather than direction, both GALNT18-to-partner and partner-to-GALNT18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by GALNT18-low versus GALNT18-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT18→partner) and Y-score (partner→GALNT18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.354	+1.415	.003	.043	3	3
UCEC	EGFR_pY1068 →	-0.181	-2.415	.031	.003	3	2
UCEC	Gab2 →	+0.252	+1.874	.035	.049	3	2
UCEC	JNK2 →	+0.203	+1.321	.002	.029	3	2
UCEC	MEK1 →	+0.386	+2.247	.001	.001	3	2
UCEC	mTOR_pS2448 →	-0.145	-1.828	.003	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

ASNS by GALNT18 expression — UCEC

Explore this box plot interactively →