GALNT18

Across TCGA cell cohorts, GALNT18 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GALNT18-associated genes across cancer lineages are AKAP4, NXF5, and RFPL3. Each is linked with GALNT18 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT18-to-partner and partner-to-GALNT18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AKAP4 grouped by GALNT18-low versus GALNT18-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT18→partner) and Y-score (partner→GALNT18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	AKAP4 →	+0.012	+4.959	<.001	<.001	3	2
LARGE_INTESTINE	NXF5 →	+0.032	+4.467	<.001	.004	3	1
LARGE_INTESTINE	RFPL3 →	+0.045	+4.095	<.001	.009	3	1
LARGE_INTESTINE	OR2M5 →	+0.016	+4.415	<.001	.007	3	1
LARGE_INTESTINE	GKN1 →	+0.045	+4.095	.002	.009	3	1
LARGE_INTESTINE	TRIM64B →	+0.004	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

AKAP4 by GALNT18 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →