GALNT15

Across TCGA cell cohorts, GALNT15 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GALNT15-associated genes across cancer lineages are SPATA31D1, IFNG, and WFDC12. Each is linked with GALNT15 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT15-to-partner and partner-to-GALNT15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA31D1 grouped by GALNT15-low versus GALNT15-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT15→partner) and Y-score (partner→GALNT15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SPATA31D1 →	+0.843	+5.643	<.001	.002	3	2
BLOOD_Leukemia	IFNG →	+0.220	+4.152	<.001	.009	3	1
BLOOD_Leukemia	WFDC12 →	+0.249	+4.874	<.001	.002	3	1
BLOOD_Leukemia	DEFB4A →	+0.123	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	CFHR2 →	+0.296	+4.539	<.001	.007	3	1
LUNG_NSCLC_LUAD	CPA1 →	+0.217	+3.866	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

SPATA31D1 by GALNT15 expression — LUNG_SCLC

Explore this box plot interactively →