GALNT14

Across TCGA patient cohorts, GALNT14 mutation is significantly associated with the RNA expression of many other genes, with 5,307 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT14-associated genes across cancer lineages are ZWINT, UFD1, and TRIP13. Each is linked with GALNT14 in more than 3 cancer types. Because this analysis shows association rather than direction, both GALNT14-to-partner and partner-to-GALNT14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZWINT grouped by GALNT14-low versus GALNT14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT14→partner) and Y-score (partner→GALNT14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZWINT →	+0.791	+1.999	<.001	<.001	3	4
UCEC	UFD1 →	+0.444	+2.053	<.001	<.001	3	4
UCEC	TRIP13 →	+0.500	+1.530	.004	.004	3	4
UCEC	MTHFD2 →	+0.577	+1.823	.001	.002	3	4
UCEC	ELAC2 →	+0.447	+2.584	<.001	<.001	3	4
UCEC	BIRC5 →	+0.763	+2.032	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,307 associations by consensus.

ZWINT by GALNT14 expression — UCEC

Explore this box plot interactively →