GALNT11

Across TCGA patient cohorts, GALNT11 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT11-associated genes across cancer lineages are MEK1, Fibronectin, and INPP4B. Each is linked with GALNT11 in more than 2 cancer types. Because this analysis shows association rather than direction, both GALNT11-to-partner and partner-to-GALNT11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by GALNT11-low versus GALNT11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT11→partner) and Y-score (partner→GALNT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.372	+2.070	.003	.001	3	3
UCEC	Fibronectin →	-0.246	-1.492	.031	.027	3	2
UCEC	INPP4B →	-0.282	-2.000	.012	.029	3	2
UCEC	Ku80 →	+0.190	+1.453	.020	.015	3	2
UCEC	p90 RSK →	+0.153	+1.495	.020	.034	3	2
UCEC	ATM →	-0.448	-2.102	.004	.016	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

MEK1 by GALNT11 expression — UCEC

Explore this box plot interactively →