GALNT11

Across TCGA cell cohorts, GALNT11 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,435 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GALNT11-associated GO terms across cancer lineages are Positive regulation of isotype switching to IgG isotypes, Notch receptor processing, and Fatty acid catabolic process. Each is linked with GALNT11 in more than 10 cancer types. Because this analysis shows association rather than direction, both GALNT11-to-partner and partner-to-GALNT11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of isotype switching to IgG isotypes grouped by GALNT11-low versus GALNT11-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT11→partner) and Y-score (partner→GALNT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of isotype switching to IgG isotypes →	+0.144	+0.896	.008	.006	3	11
OESOPHAGUS	Notch receptor processing →	+0.108	+0.854	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Fatty acid catabolic process →	+0.070	+0.879	.001	<.001	3	11
BONE	Intraciliary retrograde transport →	+0.101	+1.072	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Regulation of isotype switching to IgG isotypes →	+0.140	+1.224	.002	.001	3	10
SKIN	Alcohol metabolic process →	+0.059	+1.069	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,435 associations by consensus.

Positive regulation of isotype switching to IgG isotypes by GALNT11 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →