GALNT11

Across TCGA cell cohorts, GALNT11 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GALNT11-associated genes across cancer lineages are IFNG, OOSP4A, and PRLHR. Each is linked with GALNT11 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT11-to-partner and partner-to-GALNT11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNG grouped by GALNT11-low versus GALNT11-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT11→partner) and Y-score (partner→GALNT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	IFNG →	+0.078	+5.321	<.001	.005	3	1
CNS	OOSP4A →	+0.074	+5.321	<.001	.005	3	1
SKIN	PRLHR →	+0.015	+5.022	<.001	.002	3	1
SKIN	RESP18 →	+0.024	+4.415	<.001	.007	3	1
UPPER_AERODIGESTIVE_TRACT	GPIHBP1 →	+0.030	+3.129	.004	.007	3	1
UPPER_AERODIGESTIVE_TRACT	CEACAM21 →	+0.028	+3.691	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

IFNG by GALNT11 expression — CNS

Explore this box plot interactively →