GALNT10

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GALNT10 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT10-associated genes across cancer lineages are 14-3-3_beta, ERK2, and p62 Lck ligand. Each is linked with GALNT10 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT10-to-partner and partner-to-GALNT10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by GALNT10-low versus GALNT10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT10→partner) and Y-score (partner→GALNT10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEC14-3-3_beta →-0.090-1.780.007.02432
UCECERK2 →+0.200+3.700.001.00132
UCECp62 Lck ligand →+0.468+2.584<.001<.00132
UCECPDCD4 →-0.338-2.000.032.02932
UCECTuberin_pT1462 →+0.185+1.321.016.02932
UCECASNS →+0.431+1.847<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

14-3-3_beta by GALNT10 expression — UCEC

Box plot of 14-3-3_beta in GALNT10-low vs GALNT10-high samples in UCEC.

Explore this box plot interactively →

Exploration