GALNT1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, GALNT1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated GALNT1 data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher GALNT1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated GALNT1 expression acts as an unfavorable survival marker.

CCRCC, LSCC, and PDAC are the cancer types where GALNT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSMedianAll0.6251.000.00232view →
LSCCDFSTertileAll0.8870.999.0068view →
PDACDFSTertileAll0.3140.488.0335view →
LUADOSQuartileII,III,IV0.4850.863.0395view →
GBMDFSQuartileAll0.7560.879.0272view →
HNSCDFSTertileIII,IV0.5410.771.0461view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

GALNT1–CCRCC (OS)

Kaplan–Meier survival curve for GALNT1 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration