GALNT1

Across TCGA patient cohorts, GALNT1 mutation is significantly associated with the RNA expression of many other genes, with 4,138 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT1-associated genes across cancer lineages are RN7SL284P, CRYBB2P1, and HIRA. Each is linked with GALNT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GALNT1-to-partner and partner-to-GALNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL284P grouped by GALNT1-low versus GALNT1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT1→partner) and Y-score (partner→GALNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RN7SL284P →	+0.148	+5.108	<.001	.008	3	3
UCEC	CRYBB2P1 →	+0.436	+2.072	<.001	<.001	3	2
UCEC	HIRA →	+0.527	+2.343	<.001	<.001	3	2
UCEC	FBXO7 →	+0.462	+2.343	<.001	<.001	3	2
UCEC	SAMM50 →	+0.366	+1.828	.003	<.001	3	2
UCEC	L3MBTL2 →	+0.460	+3.010	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,138 associations by consensus.

RN7SL284P by GALNT1 expression — LIHC

Explore this box plot interactively →