GALNT1

Across TCGA patient cohorts, GALNT1 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT1-associated genes across cancer lineages are FoxM1, Annexin-1, and S6_pS240_S244. Each is linked with GALNT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT1-to-partner and partner-to-GALNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by GALNT1-low versus GALNT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT1→partner) and Y-score (partner→GALNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.233	+1.594	.004	.021	3	2
UCEC	Annexin-1 →	+0.521	+2.107	.001	.002	3	2
UCEC	S6_pS240_S244 →	+0.425	+3.000	.001	<.001	3	2
UCEC	VHL →	-0.763	-1.440	<.001	.022	3	2
UCEC	14-3-3_beta →	-0.091	-2.780	.004	.003	3	1
UCEC	eEF2 →	+0.228	+1.700	.046	.040	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

FoxM1 by GALNT1 expression — UCEC

Explore this box plot interactively →