GALNT1

Across TCGA cell cohorts, GALNT1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GALNT1-associated genes across cancer lineages are CCER1, PRAMEF33, and C9. Each is linked with GALNT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT1-to-partner and partner-to-GALNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCER1 grouped by GALNT1-low versus GALNT1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT1→partner) and Y-score (partner→GALNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CCER1 →	+0.016	+5.754	<.001	.002	3	1
BLOOD_Lymphoma	PRAMEF33 →	+0.013	+5.643	<.001	.002	3	1
BLOOD_Leukemia	C9 →	+1.076	+3.775	<.001	.004	3	1
BLOOD_Leukemia	LRIT1 →	+0.027	+3.684	<.001	.004	3	1
BLOOD_Leukemia	DEFB108B →	+0.105	+3.684	<.001	.004	3	1
BLOOD_Leukemia	PRR30 →	+0.017	+3.684	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

CCER1 by GALNT1 expression — CNS

Explore this box plot interactively →