GALNS

Across TCGA patient cohorts, GALNS protein abundance is significantly associated with the RNA expression of many other genes, with 9,674 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GALNS-associated genes across cancer lineages are RPN2, FAM20A, and COL5A1. Each is linked with GALNS in more than 4 cancer types. Because this analysis shows association rather than direction, both GALNS-to-partner and partner-to-GALNS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GALNS versus RPN2 in LSCC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNS→partner) and Y-score (partner→GALNS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RPN2 →	+0.412	+0.381	<.001	<.001	3	5
GBM	FAM20A →	+0.577	+0.274	<.001	.005	3	4
GBM	COL5A1 →	+1.125	+0.253	<.001	<.001	3	4
HNSC	ITGA11 →	+0.836	+0.320	<.001	<.001	3	4
GBM	RUNX1 →	+0.788	+0.404	<.001	<.001	3	4
LSCC	TOM1 →	+0.279	+0.318	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,674 associations by consensus.

GALNS vs RPN2 — LSCC

Explore this scatter interactively →