GALNS

Across TCGA cell cohorts, GALNS RNA expression is significantly associated with the go_rna of many other GO terms, with 4,508 significant associations in total. CNS shows the largest number of these associations.

The most reproducible GALNS-associated GO terms across cancer lineages are Glycoprotein catabolic process, Negative regulation of calcium ion export across plasma membrane, and Proteoglycan catabolic process. Each is linked with GALNS in more than 15 cancer types. Because this analysis shows association rather than direction, both GALNS-to-partner and partner-to-GALNS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycoprotein catabolic process grouped by GALNS-low versus GALNS-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNS→partner) and Y-score (partner→GALNS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Glycoprotein catabolic process →	+0.145	+0.809	.007	.008	3	15
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.073	+1.055	.006	.002	3	15
BONE	Proteoglycan catabolic process →	+0.166	+0.864	.009	.006	2	16
BONE	Vacuole organization →	+0.049	+1.063	<.001	<.001	3	14
BONE	Chondroitin sulfate proteoglycan catabolic process →	+0.180	+1.205	.001	<.001	3	14
BONE	Lysosome organization →	+0.064	+1.038	.002	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,508 associations by consensus.

Glycoprotein catabolic process by GALNS expression — BONE

Explore this box plot interactively →