GALK2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GALK2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,809 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GALK2-associated genes across cancer lineages are DBF4B, CENPE, and POLA2. Each is linked with GALK2 in more than 6 cancer types. Because this analysis shows association rather than direction, both GALK2-to-partner and partner-to-GALK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GALK2 versus DBF4B in BRCA, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALK2→partner) and Y-score (partner→GALK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCADBF4B →-0.757-0.385<.001<.00137
CCRCCCENPE →-0.811-0.336<.001<.00136
LSCCPOLA2 →-0.462-0.228.001<.00136
LUADCCNF →-0.603-0.243<.001<.00136
GBMCKAP2L →-0.996-0.362<.001<.00136
LUADUHRF1 →-0.829-0.264.004.00436
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,809 associations by consensus.

GALK2 vs DBF4B — BRCA

Per-sample scatter of GALK2 vs DBF4B in BRCA (Pearson r = -0.43).

Explore this scatter interactively →

Exploration