GALK2

Across TCGA cell cohorts, GALK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,880 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GALK2-associated GO terms across cancer lineages are Tricarboxylic acid cycle, Circadian sleep/wake cycle, and Ubiquitin-dependent protein catabolic process via the N-end rule pathway. Each is linked with GALK2 in more than 11 cancer types. Because this analysis shows association rather than direction, both GALK2-to-partner and partner-to-GALK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tricarboxylic acid cycle grouped by GALK2-low versus GALK2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GALK2→partner) and Y-score (partner→GALK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Tricarboxylic acid cycle →	+0.173	+0.957	<.001	<.001	3	12
LIVER	Circadian sleep/wake cycle →	+0.185	+1.282	<.001	<.001	2	10
UPPER_AERODIGESTIVE_TRACT	Ubiquitin-dependent protein catabolic process via the N-end rule pathway →	+0.087	+0.859	<.001	.002	3	9
LIVER	Galactose metabolic process →	+0.165	+1.156	.006	.008	3	8
LUNG_NSCLC_LUAD	Tricarboxylic acid metabolic process →	+0.107	+0.509	<.001	<.001	3	8
BLOOD_Leukemia	Regulation of B cell proliferation →	-0.105	-0.669	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,880 associations by consensus.

Tricarboxylic acid cycle by GALK2 expression — LIVER

Explore this box plot interactively →