GALK2

Across TCGA cell cohorts, GALK2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GALK2-associated genes across cancer lineages are GJD2, KRTAP10-2, and C9orf92. Each is linked with GALK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALK2-to-partner and partner-to-GALK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GJD2 grouped by GALK2-low versus GALK2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALK2→partner) and Y-score (partner→GALK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GJD2 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	KRTAP10-2 →	+0.044	+2.994	.001	.006	3	1
BLOOD_Leukemia	C9orf92 →	+0.147	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

GJD2 by GALK2 expression — LARGE_INTESTINE

Explore this box plot interactively →