GALE

Across TCGA patient cohorts, GALE RNA expression is significantly associated with the protein abundance of many other proteins, with 10,912 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GALE-associated proteins across cancer lineages are JPT2, NUDC, and EPS8L2. Each is linked with GALE in more than 6 cancer types. Because this analysis shows association rather than direction, both GALE-to-partner and partner-to-GALE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GALE versus JPT2 in UCEC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GALE→partner) and Y-score (partner→GALE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JPT2 →	+0.347	+0.977	<.001	<.001	3	7
COAD	NUDC →	+0.421	+0.562	<.001	<.001	3	7
HNSC	EPS8L2 →	+0.481	+0.865	<.001	<.001	3	5
PDAC	ESPN →	+0.964	+0.587	<.001	.001	3	5
LSCC	KIAA1522 →	+0.414	+0.801	<.001	<.001	3	5
BRCA	LYPLA2 →	+0.296	+0.576	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,912 associations by consensus.

GALE vs JPT2 — UCEC

Explore this scatter interactively →