GALE

Across TCGA cell cohorts, GALE RNA expression is significantly associated with the go_rna of many other GO terms, with 4,090 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GALE-associated GO terms across cancer lineages are Renal vesicle formation, Metanephric renal vesicle formation, and Positive regulation of exosomal secretion. Each is linked with GALE in more than 8 cancer types. Because this analysis shows association rather than direction, both GALE-to-partner and partner-to-GALE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Renal vesicle formation grouped by GALE-low versus GALE-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GALE→partner) and Y-score (partner→GALE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Renal vesicle formation →	-1.132	-0.911	.002	.005	3	9
STOMACH	Metanephric renal vesicle formation →	-1.132	-0.911	.002	.005	3	9
LUNG_NSCLC_LUSC	Positive regulation of exosomal secretion →	+0.119	+1.587	<.001	.001	3	9
LIVER	Bradykinin catabolic process →	+0.224	+0.862	.001	.001	3	9
BLOOD_Leukemia	Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage →	-0.064	-0.615	<.001	<.001	3	9
LUNG_SCLC	GDP-mannose biosynthetic process →	+0.138	+1.210	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,090 associations by consensus.

Renal vesicle formation by GALE expression — STOMACH

Explore this box plot interactively →