GAL

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GAL protein abundance is significantly associated with the RNA expression of many other genes, with 335 significant associations in total. COAD shows the largest number of these associations.

The most reproducible GAL-associated genes across cancer lineages are SPRTN, TRIP11, and SLC32A1. Each is linked with GAL in more than 1 cancer types. Because this analysis shows association rather than direction, both GAL-to-partner and partner-to-GAL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAL versus SPRTN in COAD, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAL→partner) and Y-score (partner→GAL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADSPRTN →+0.321+0.616.003.00431
COADTRIP11 →+0.398+0.667.009.00431
COADSLC32A1 →+0.015+0.772.006.00131
COADPPP1R16B →+0.411+0.478.007.00431
COADCPPED1 →+0.389+0.677<.001<.00131
COADEBI3 →+0.524+0.697<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 335 associations by consensus.

GAL vs SPRTN — COAD

Per-sample scatter of GAL vs SPRTN in COAD (Pearson r = 0.31).

Explore this scatter interactively →

Exploration