GAGE2E

Across TCGA patient cohorts, GAGE2E RNA expression is significantly associated with the go_rna of many other GO terms, with 3,920 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GAGE2E-associated GO terms across cancer lineages are Positive regulation of telomerase RNA localization to Cajal body, Positive regulation of telomerase activity, and Peptidyl-lysine modification. Each is linked with GAGE2E in more than 6 cancer types. Because this analysis shows association rather than direction, both GAGE2E-to-partner and partner-to-GAGE2E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of telomerase RNA localization to Cajal body grouped by GAGE2E-low versus GAGE2E-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GAGE2E→partner) and Y-score (partner→GAGE2E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of telomerase RNA localization to Cajal body →	+0.128	+0.045	<.001	.001	3	7
STAD	Positive regulation of telomerase activity →	+0.120	+0.062	<.001	<.001	3	6
UCEC	Peptidyl-lysine modification →	+0.142	+0.053	<.001	.003	3	6
UCEC	Regulation of microtubule cytoskeleton organization →	+0.133	+0.041	<.001	.003	3	6
UCEC	Positive regulation of cell cycle process →	+0.153	+0.026	<.001	.003	3	6
UCEC	Amino acid activation →	+0.139	+0.051	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,920 associations by consensus.

Positive regulation of telomerase RNA localization to Cajal body by GAGE2E expression — STAD

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