GAGE2E

Across TCGA cell cohorts, GAGE2E RNA expression is significantly associated with the go_rna of many other GO terms, with 428 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GAGE2E-associated GO terms across cancer lineages are Postsynaptic cytoskeleton organization, Epicardium-derived cardiac fibroblast cell differentiation, and Epicardium-derived cardiac fibroblast cell development. Each is linked with GAGE2E in more than 3 cancer types. Because this analysis shows association rather than direction, both GAGE2E-to-partner and partner-to-GAGE2E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Postsynaptic cytoskeleton organization grouped by GAGE2E-low versus GAGE2E-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GAGE2E→partner) and Y-score (partner→GAGE2E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Postsynaptic cytoskeleton organization →	-0.100	-1.692	.001	.008	2	4
LIVER	Epicardium-derived cardiac fibroblast cell differentiation →	-0.208	-3.388	.003	.001	3	3
LIVER	Epicardium-derived cardiac fibroblast cell development →	-0.208	-3.388	.003	.001	3	3
SKIN	Positive regulation of Golgi to plasma membrane protein transport →	-0.048	-1.854	.003	.008	3	3
SKIN	Purine nucleotide biosynthetic process →	+0.044	+2.724	.001	.003	3	3
OESOPHAGUS	Regulation of mitochondrial translation →	+0.079	+2.238	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 428 associations by consensus.

Postsynaptic cytoskeleton organization by GAGE2E expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →