Across TCGA patient cohorts, GAGE10 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GAGE10-associated genes across cancer lineages are LINC02220, NUTF2P8, and MIR6133. Each is linked with GAGE10 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAGE10-to-partner and partner-to-GAGE10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAGE10→partner) and Y-score (partner→GAGE10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC02220 →	+0.604	+4.730	<.001	.003	3	1
UCEC	NUTF2P8 →	+0.305	+4.982	<.001	.009	3	1
UCEC	MIR6133 →	+0.953	+4.982	<.001	.009	3	1
UCEC	MIR8058 →	+0.856	+5.081	<.001	.008	3	1
LUSC	RNA5SP234 →	+0.455	+7.924	<.001	.008	3	1
LUSC	RNA5SP31 →	+0.705	+7.924	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

GAGE10 survival (RNA) · tumor vs normal (RNA) · all GAGE10 data types