Across TCGA patient cohorts, GAGE1 protein abundance is significantly associated with the RNA expression of many other genes, with 284 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GAGE1-associated genes across cancer lineages are GAGE2A, CEACAM5, and FOXRED1. Each is linked with GAGE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAGE1-to-partner and partner-to-GAGE1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAGE1→partner) and Y-score (partner→GAGE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GAGE2A →	+4.210	+2.960	<.001	<.001	3	2
HNSC	CEACAM5 →	+3.494	+2.711	<.001	.002	3	1
HNSC	FOXRED1 →	+0.719	+1.975	<.001	.001	3	1
HNSC	CTAG2 →	+4.130	+2.248	<.001	.002	3	1
HNSC	KCNH5 →	+0.248	+2.754	.002	.001	3	1
HNSC	ANKFN1 →	+0.625	+1.672	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 284 associations by consensus.

Exploration

GAGE1 survival (RNA) · tumor vs normal (RNA) · all GAGE1 data types