Across TCGA patient cohorts, GAGE1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GAGE1-associated genes across cancer lineages are RNU6-206P, MIR1229, and RNA5SP41. Each is linked with GAGE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAGE1-to-partner and partner-to-GAGE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAGE1→partner) and Y-score (partner→GAGE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-206P →	+0.485	+6.912	<.001	<.001	3	1
LUAD	MIR1229 →	+0.451	+5.554	<.001	.004	3	1
LUAD	RNA5SP41 →	+0.337	+5.410	.003	.005	3	1
LUAD	ELOCP30 →	+0.137	+6.197	<.001	.001	3	1
LUAD	RNU7-165P →	+0.503	+5.888	<.001	.002	3	1
LUAD	CYCTP →	+0.126	+6.197	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

GAGE1 survival (RNA) · tumor vs normal (RNA) · all GAGE1 data types