GADD45GIP1

Across TCGA patient cohorts, GADD45GIP1 mutation is significantly associated with the RNA expression of many other genes, with 215 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GADD45GIP1-associated genes across cancer lineages are TMEM269, RNA5SP411, and SLC20A1P3. Each is linked with GADD45GIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GADD45GIP1-to-partner and partner-to-GADD45GIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM269 grouped by GADD45GIP1-low versus GADD45GIP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GADD45GIP1→partner) and Y-score (partner→GADD45GIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TMEM269 →	+0.231	+2.617	<.001	.006	3	1
UCEC	RNA5SP411 →	+1.216	+2.393	<.001	.002	3	1
BLCA	SLC20A1P3 →	+0.049	+7.640	<.001	.009	3	1
BLCA	RNU6-1040P →	+0.343	+7.640	<.001	.009	3	1
UCEC	DFFA →	+0.561	+3.217	.001	.009	3	1
UCEC	RPP14 →	+0.389	+3.732	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 215 associations by consensus.

TMEM269 by GADD45GIP1 expression — UCEC

Explore this box plot interactively →