GADD45GIP1

Across TCGA patient cohorts, GADD45GIP1 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GADD45GIP1-associated genes across cancer lineages are Caspase-8, MEK1, and Cyclin-B1. Each is linked with GADD45GIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GADD45GIP1-to-partner and partner-to-GADD45GIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-8 grouped by GADD45GIP1-low versus GADD45GIP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GADD45GIP1→partner) and Y-score (partner→GADD45GIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-8 →	-0.306	-3.143	.026	.018	3	1
UCEC	MEK1 →	+0.491	+3.169	.014	.020	2	1
UCEC	Cyclin-B1 →	+0.614	+3.169	.046	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Caspase-8 by GADD45GIP1 expression — UCEC

Explore this box plot interactively →